Celiac disease occurs as a result of genetic
factors, gluten and other environmental
factors. The genes necessary for the disease
to occur are HLA DQ2 or DQ8. However,
these genes are common, occurring in about
30% of the general population. There are
many other genes that have been linked to
the disease. The known environmental
factors that may contribute to the development
of the disease include, GI infections, timing and
gluten consumption, and birth by C section.
Celiac disease can develop at any age from
infancy to old age and occurs equally in
males and females.